A specific quirk of Cubase 5 is that the "Loading Audio Driver" bar during startup tells you everything. If the bar stutters or freezes, the driver is conflicting with another application (like a web browser playing YouTube).
To configure the audio driver in Cubase 5, follow these steps: cubase 5 audio driver
A major frustration with legacy ASIO is that it "locks" the sound card. You cannot hear a YouTube tutorial and Cubase 5 at the same time. A specific quirk of Cubase 5 is that